Compounds obtained from salvia species having antiviral activity

Details Compounds obtained from salvia species having antiviral activity Compounds obtained from salvia species having antiviral activity

1999-06-25

2000-03-28

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514533, 424 7837, 4241951, A01N 3710, A61K 31765

Patent

active

060432764

ABSTRACT:
Compositions are provided containing molecules having at least one moiety from .beta.-(3,4-dihydroxyphenyl) lactic acid and/or caffeic acid, which are found in extracts from the plant genus Salvia, said moieties being of the formula: ##STR1## the active agents having a molecular weight of at least 190 daltons. A class of preferred agents are those which are conjugated to form dimers, trimers, tetramers and larger polymers containing said moieties, with the most preferred being salvianolic acid dimers, trimers, tetramers and larger polymers. The compounds and compositions may be administered in pharmaceutically acceptable carriers and excipients systemically or locally to treat viral infections.

REFERENCES:
Li, "Water Soluble Active Components of Salvia miltiorrhiza and Related Plants", Journal of Chinese Pharmaceutical Sciences 6 (2), pp. 57-64, Jan. 1997.

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