Compounds modulating sister chromatid separation and method...

Details Compounds modulating sister chromatid separation and method... Compounds modulating sister chromatid separation and method...

2000-02-15

2008-08-12

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

C435S004000, C435S183000, C435S219000, C435S226000, C530S350000

Reexamination Certificate

active

07410774

ABSTRACT:
Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.

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NCBI Entrez, GenBank Report, Accession No

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