Compounds, methods of screening, and in vitro and in vivo...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S023720, C536S024500

Reexamination Certificate

active

07449450

ABSTRACT:
Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; Compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; Methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; Methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; Pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.

REFERENCES:
patent: 6204251 (2001-03-01), Cuthbertson
Cinatl et al., “Modulatory effects of human cytomegalovirus infection on malignant properties of cancer cells,” Intervirology. 1996;39(4):259-69.
Cinatl et al., “Persistent Human Cytomegalovirus Infection Induces Drug Resistance and Alteration of Programmed Cell Death in Human Neuroblastoma Cells,” Cancer Research, 58, pp. 367-372 (1998).
Azad et al., “Antiviral activity of a phosphorothioate oligonucleotide complementary to human cytomegalovirus RNA when used in combination with antiviral nucleoside analogs,” Antiviral Res. Oct. 1995;28(2):101-11.
Crooke, “Antisense therapeutics,” Biotechnol Genet Eng Rev. 1998;15:121-57.
Mulamba et al., “Human Cytomegalovirus Mutant with Sequence-Dependent Resistance to the Phosphorothioate Oligonucleotide Fomivirsen (ISIS 2922),” Antimicrobial Agents and Chemotherapy, vol. 42, No. 4, pp. 971-973 (1998).
Leeds et al., “Pharmacokinetics of a Potential Human Cytomegalovirus Therapeutic, A Phosphorothioate Oligonucleotide, After Intravitreal Injection in the Rabbit,” Drug Metabolism and Disposition, vol. 25, No. 8, pp. 921-926 (1997).
Schleiss et al., “Progress toward an elusive goal: current status of cytomegalovirus vaccines,” Expert. Rev. Vaccines 4(3), 381-406 (2005).
Temsamani et al. “Antisense approach for the treatment of cytomegalovirus infection.” Expert Opinion on Investigational Drugs 6(6): 1157-1167, 1997.
Kronenwett et al. “Antisense strategies for the treatment of hematological malignancies and solid tumors.” Ann. Hematol. 77: 1-12, 1998.
Cinatl et al. “Modulatory effects of human cytomegalovirus infection on malignant properties of cancer cells.” intervirology 39(4): 259-269, 1996.
Pari et al,Antimicrobial Agents and Chemotherapy, 39(5):1157-1161 (1995).
Smith et al,J. of Virology, 69(3):1925-1931 (1995).

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