Compounds, methods and pharmaceutical compositions for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S235000, C514S248000

Reexamination Certificate

active

07601719

ABSTRACT:
The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.

REFERENCES:
patent: 6291425 (2001-09-01), Li et al.
Gagne et al. Current Opinion in Cell Biology 2006, 18:145-151.
Chalmers (TiPS vol. 17, pp. 166-172 Apr. 1996).
Combs et al. Journal of Heterocyclic Chemistry, 1989, vol. 26, 1885-1886.
E.S. Newlands, et al., “Temozolomide: A Review of its Discovery, Chemical Properties, Pre-clinical Development and Clinical Trials,”Cancer Treatment Reviews(1997) 23, pp. 35-61.

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