Compounds having selective activity for Retinoid X Receptors, an

Details Compounds having selective activity for Retinoid X Receptors, an Compounds having selective activity for Retinoid X Receptors, an

1995-06-07

1998-07-14

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562501, 554220, 554221, C07C 6336

Patent

active

057806764

ABSTRACT:
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and poiyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.

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