Compounds having inhibitory activity against...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S054000, C536S122000

Reexamination Certificate

active

07666845

ABSTRACT:
The invention is directed to compounds of the formula (I) described herein, a pharmaceutically acceptable salt thereof, or a prodrug thereof, and pharmaceutical compositions and methods of treatment.

REFERENCES:
patent: 5424406 (1995-06-01), Tsujihara et al.
patent: 5731292 (1998-03-01), Tsujihara et al.
patent: 5830873 (1998-11-01), Tsujihara et al.
patent: 6414126 (2002-07-01), Ellsworth et al.
patent: 6515117 (2003-02-01), Ellsworth et al.
patent: 6562791 (2003-05-01), Maurya et al.
patent: 2001/0041674 (2001-11-01), Tomiyama et al.
patent: 2002/0052326 (2002-05-01), Washburn
patent: 2002/0111315 (2002-08-01), Washburn et al.
patent: 2003/0064935 (2003-04-01), Gougoutas
patent: 2003/0087843 (2003-05-01), Washburn
patent: 2003/0114390 (2003-06-01), Washburn et al.
patent: 2004/0053855 (2004-03-01), Fujikura et al.
patent: 2004/0063646 (2004-04-01), Fujikura et al.
patent: 2004/0110936 (2004-06-01), Ohsumi et al.
patent: 2004/0116357 (2004-06-01), Fushimi et al.
patent: 2004/0132669 (2004-07-01), Nishimura et al.
patent: 2004/0138143 (2004-07-01), Glombik et al.
patent: 2004/0259819 (2004-12-01), Frick et al.
patent: 2005/0014704 (2005-01-01), Frick et al.
patent: 2005/0032711 (2005-02-01), Patel et al.
patent: 2005/0032712 (2005-02-01), Urbanski
patent: 2005/0037980 (2005-02-01), Rybczynski et al.
patent: 2005/0037981 (2005-02-01), Beavers et al.
patent: 2005/0233988 (2005-10-01), Nomura et al.
patent: 2006/0035841 (2006-02-01), Eckhardt et al.
patent: 2006/0122126 (2006-06-01), Imamura et al.
patent: 2006/0217323 (2006-09-01), Patel et al.
patent: 2006/0229260 (2006-10-01), Rybczynski et al.
patent: 2006/0234954 (2006-10-01), Urbanski
patent: 2006/0293251 (2006-12-01), Urbanski et al.
patent: 2007/0060545 (2007-03-01), Nomura et al.
patent: 2008/0027122 (2008-01-01), Nomura et al.
patent: 2 494 177 (2004-02-01), None
patent: 1 528 066 (2005-05-01), None
patent: 2001-288178 (2001-10-01), None
patent: 2003-12686 (2003-01-01), None
patent: WO 01/27128 (2001-04-01), None
patent: WO 01/68660 (2001-09-01), None
patent: WO 01/74834 (2001-10-01), None
patent: WO 01/74835 (2001-10-01), None
patent: WO 02/053573 (2002-07-01), None
patent: WO 02/068439 (2002-09-01), None
patent: WO 02/068440 (2002-09-01), None
patent: WO 02/083066 (2002-10-01), None
patent: WO 02/088157 (2002-11-01), None
patent: WO 03/011880 (2003-02-01), None
patent: WO 03/020737 (2003-03-01), None
patent: WO 03/099836 (2003-12-01), None
patent: WO 2004/007517 (2004-01-01), None
patent: WO 2004/013118 (2004-02-01), None
patent: WO 2004/014931 (2004-02-01), None
patent: WO 2004/019958 (2004-03-01), None
patent: WO 2004/052903 (2004-06-01), None
patent: WO 2004/080990 (2004-09-01), None
patent: WO 2005/012326 (2005-02-01), None
patent: WO 2006/010557 (2006-02-01), None
patent: WO 2008/013322 (2008-01-01), None
Unger et al. “Hyperglycemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes” Diabetologia, vol. 28, p. 119-121 (1985).
Rossetti et al. “Glucose Toxicity”; Diabetes Care, vol. 13, p. 610-630 (1990).
Rossetti et al. Correction of Hyperglycemia with Phlorizin Normalizes Tissue Sensitivity to Insulin in diabetic rats Journal of Clinical Investigation, vol. 79, p. 1510-1515 (1987).
Rossetti et al. Effect of Chronic Hyperglycemia on In Vivo Insulin Secretion in Partially Pancreatectomized Rats Journal of Clinical Investigation, vol. 80, p. 1037-1044 (1987).
Kahn et al. “Normalization of Blood Glucose in Diabetic Rats with Phlorizin Treatment Reverses Insulin-resistant Glucose Transport in Adipose Cells without Restoring Glucose Transporter Gene Expression” Journal of Clinical Investigation, vol. 87, p. 561-570 (1991).
Tsujihara et al. “Na+ Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4′-Dehydroxyphlorizin Derivatives Substituted on the B Ring” Journal of Medicinal Chemistry, vol. 42, p. 5311-5324 (1999).
Arakawa et al, Improved diabetic syndrome in C57BL/KsJ-db/db Mice By Oral Administration of the Na+− Glucose Cotransporter Inhibitor T-1095: British Journal of Pharmacology, vol. 132, p. 578-586 (2001).
Ueta et al. “Long-term treatment with the Na+−glucose contransporter inhibitor T1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats” Life Sci., 76(23): 2655-68 (2005), etc.
Roshan Ahmad et al., Nucleosides, Nucleotides & Nucleic Acids, vol. 20, No. 9, (2001), pp. 1671-1682.
Khosrow Zamani et al., Journal of the Chinese Chemical Society, vol. 49, (2002), pp. 1041-1044.
Galal T. Maatooq et al., Phytochemistry, vol. 44, No. 1, (Jan. 1997), pp. 187-190.
Hongu et al., Chem. Pharm. Bull, vol. 46, No. 1, pp. 22-33, (1998).
PCT International Search Report dated Apr. 16, 2008 for PCT/US2007/086247 which relates to U.S. Appl. No. 11/949,236.

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