Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-03-23
1990-08-28
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546164, 546165, C07D21548, A61K 3147
Patent
active
049525735
ABSTRACT:
Compounds which enhance the efficiency of the corneal endothelial fluid pump thereby promoting normal corneal function and deturgescence of swollen corneas, and methods for the compounds' synthesis are described. In addition, surgical irrigating solutions which include one or more of the compounds are discussed along with methods for their use.
REFERENCES:
patent: 3975530 (1976-08-01), Durant et al.
patent: 4375472 (1983-03-01), Durant et al.
patent: 4443432 (1984-04-01), Garabedian et al.
patent: 4550022 (1985-10-01), Garabedian et al.
Dikstein et al, Corneal Endothelial Pumping in the Presence of Insulin and GABA; Exp. Eve Res., vol. 31, pp. 239-241 (1980).
The Merch Index, pp. 746, 1342, 1343.
Andermann Guy
de Burlet Georges
Dietz Michel
LeClerc Gerard
Ruhland Beatrice
Arno James A.
Brown Gregg C.
Laboratoirs Alcon S.A.
Springer David B.
Yeager Sally S.
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