Compounds having cardiotonic activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514249, 514254, 514258, 514269, 514274, 514293, 540502, 544236, 544238, 544257, 544276, 544256, 544279, 544310, 544316, 544350, 546118, C07D48704, A61K 31435, A61K 3150, A61K 31505

Patent

active

050029444

ABSTRACT:
Compounds useful for increasing cardiotonic contractility in humans or other animals and pharmaceutical compositions including these compounds are disclosed. The compounds have the general structure: ##STR1## where A is ##STR2## R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.9, and R.sub.10 are H, lower alkyl of 1-4 carbon atoms, phenyl, substituted phenyl, phenyl lower alkyl of 1-4 carbon atoms or substituted phenyl lower alkyl of 1-4 carbon atoms; and n is 0 or 1.

REFERENCES:
patent: 4026891 (1977-05-01), Austel
patent: 4578386 (1986-03-01), Lee
patent: 4710507 (1987-12-01), Campbell
patent: 4859672 (1989-08-01), Spada

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