Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1995-06-07
1998-02-17
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514716, 560159, 564237, 564240, A61K 31155, C07C27902
Patent
active
057191875
ABSTRACT:
Guanidine derivatives are provided useful for promoting growth, repair and regeneration of a neuronal axon and for treating neuropathies and myopathies. The compounds have the formula: ##STR1## wherein R.sub.1 is an isopropyl radical, a benzyl radical which is optionally substituted by one or more (C.sub.1 -C.sub.6)alkoxy radicals or a radical: ##STR2## R.sub.2, R.sub.3 and R.sub.4 together with the nitrogen atoms to which they are attached and the carbon atom to which the said nitrogen atoms are attached form a pyrimidine ring of formula II or a pyrimidinium ring of formula IIa: ##STR3##
REFERENCES:
patent: 2145011 (1939-01-01), Albertlandolt et al.
patent: 5262568 (1993-11-01), Weber et al.
E. Boschetti et al., "Synthesis And Pharmacologic Classification of New Hypotensive Agents", Chemical Abstracts, vol. 70, (1969).
C.M. Gupta, "Novel Class of Hypoglecemic Agents", Chemical Abstracts, vol. 75, p. 450, Column 1, (1971).
Y.-K. Kim et al., "Synthesis and Curing Study of 5--5 Ring Fused Polyimide Based on Imidazole", Macromolecules, vol. 24, No. 23, pp. 6357-6360, (1991).
Cimarusti et al., "The Synthesis And Bisdecarboxylation of Oxygenated 90(1):113-120, (1968).
Traynelis et al., "Dehydration of Alcohols, Diols, And Related Compounds in Dimethyl Sulfoxide", J. Org. Chem., vol. 28:123-129, (1963).
Koenig Herbert
Koenig Janine
Portier Marie-Madeleine
Potier Pierre
Quirosa-Guillou Catherine
Centre National De La Recherche Scientifique(CNRS)
Gupta Yogendra N.
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