Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-03-28
2009-06-02
Weddington, Kevin E (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S230800, C514S909000, C424S750000
Reexamination Certificate
active
07541356
ABSTRACT:
Phenolic compounds with a phenolic molecule to which are covalently linked an oxygen-containing group, a nitrogen or another oxygen containing group, and a C1-C4alkoxy group, obtainable from monocotyledonous plants, or by chemical synthesis, have been found to act as weight loss agents, appetite suppressants, mood enhancers and adjunctive therapy for arthritis, sleep apnea, fibromyalgia, diabetes and hyperglycemia. Additional chemical compounds of the present invention may include benzoxazinoids-cyclic hydroxyamic acids, lactams, and corresponding glucosides, which may serve as precursors to phenolic compounds. The phenolic compounds and precursors of phenolic compounds of the present invention, at concentrations suitable for human therapeutic use, may be obtained from monocotyledonous plants such as corn in their early growth states which are timely harvested for optimum yield.
REFERENCES:
patent: 3862180 (1975-01-01), Jernow et al.
patent: 3882107 (1975-05-01), Tipton et al.
patent: 4457872 (1984-07-01), Beriger et al.
patent: 4558060 (1985-12-01), Caignard et al.
patent: 4778792 (1988-10-01), Lesieur et al.
patent: 4960778 (1990-10-01), Lesieur et al.
patent: 5071863 (1991-12-01), Ito et al.
patent: 5112843 (1992-05-01), Bjostad, III et al.
patent: 5147883 (1992-09-01), Aichaioui et al.
patent: 5179091 (1993-01-01), Lesieur et al.
patent: 5182278 (1993-01-01), Lesieur et al.
patent: 5196434 (1993-03-01), Tavernet et al.
patent: 5240919 (1993-08-01), Yous et al.
patent: 5292735 (1994-03-01), Sugimoto et al.
patent: 5296477 (1994-03-01), Taverne et al.
patent: 5300507 (1994-04-01), Yous et al.
patent: 5322843 (1994-06-01), Yous et al.
patent: 5322849 (1994-06-01), Yous et al.
patent: 5326775 (1994-07-01), Yous et al.
patent: 5386034 (1995-01-01), Yous et al.
patent: 5436348 (1995-07-01), Yous et al.
patent: 5688820 (1997-11-01), Mouithys-Mickalad et al.
patent: 5786367 (1998-07-01), Oshiro et al.
patent: 5919784 (1999-07-01), Lesieur et al.
patent: 6177422 (2001-01-01), Belliotti et al.
patent: RE37478 (2001-12-01), Strupczewski et al.
patent: 6331660 (2001-12-01), Chomet et al.
patent: 6667308 (2003-12-01), Rosenfeld et al.
patent: 2004/0038909 (2004-02-01), Chawan
patent: 683593 (1994-04-01), None
patent: 670 584 (1939-01-01), None
patent: 0478446 (1922-04-01), None
patent: 0 070 016 (1983-01-01), None
patent: 0070016 (1983-01-01), None
patent: 0 506539 (1992-09-01), None
patent: 0506539 (1992-09-01), None
Klun et al., “Concentration of Two 1,4-Benzoxazinones in Dent Corn at Various Stages of Development of the Plant and Its Relation to Resistance of the Host Plant to the European Corn Borer”, Journal of Economic Entomology, vol. 62, No. 1, pp. 214-220 (1969).
Garcia H.L., “Dermatological complications,” PubMed Abstr. 12180897;American Journal of Clinical Dermatology,3(7): 497-506, 2002.
Lee, HS., “Tyrosinase inhibitors of Pulsatilla cernua root-derived materials,” PuBMed Abstr. 11879010,Journal of Agricultural Food Chemicals,50(6): 140, 2002.
Pischon et al., “Recent developments in the treatment of obesity,” PuBMed Abstr. 12187313,Current Opinions of Nephrological Hypertension,11(5): 497-502, 2002.
Wang et al., “Hypotensive activity of the pineal indoleamine hormones melatonin, 5- methoxytryptophol and 5-methoxytryptamine,” PubMeb Abstr. 10752670,Pharmacological Toxicology,86(3): 125-8, 2000.
Katz et al., “Central obesity, depression and the hypothalamo-pituitary-adrenal axis in men and postmenopausal women,”International Journal of Obesity Related Metabolism Disorders,24: 246-51, 2000.
McGahuey et al., “The Arizona Sexual Experience Scale (ASEX): reliability and validity,”Journal of Sex&Martial Therapy,26: 25-40, 2000.
Griffen et al., “Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes,”Proceedings of Natural Academy Sciences(Washington D.C.), 96(23): 13512-13517, 1999.
Rudolf et al., “Subjective quality of life in female in-patients with depression: A longitudinal study,”International Journal of Social Psychiatry,45(4): 238-46, 1999.
Negus et al., “Reproductive strategies ofDicrostonyx groenlandicusandLemmus sibtricusin high-arctic tundra,”Canadian Journal of Zoology,76: 391-399, 1998.
Gianoli et al., “Characteristics of hydroxamic acid induction in wheat triggered by aphid infestation,”Journal of Chemical Ecology,23(12): 2695-2705, 1997.
Niemeyer et al., “Chromosomal location of genes for hydroxamic acid accumulation inTriticum aestivumL. (wheat) using wheat aneuploids and wheat substitution lines,”Heredity,79: 10-14, 1997.
Dowd et al., “Enzymatic oxidation products of allelochemicals as a basis for resistance against insects: effects on the corn leafhopperDalbulus maidis,” Natural Toxins,4: 85-91, 1996.
Cooksey, C., “A Simple One Pot Reaction of 4-Alkoxy and 4-Alkylthio-Catechols and O-Benzoquinones”,Organic Preparations and Procedures Int.,vol. 28, No. 4, 463-467, 1996.
Meek et al., “Interation of maternal photoperiod history and food type on growth and reproductive development of laboratory meadow voles (Microtus pennsylvanicus),”Physiology and Behavior,57(5): 905-11, 1995.
Bergvinson et al., “Putative role of photodimerized phenolic acids in maize resistance toOstrinia nubilalis(Lepidoptera: Pyralidae),”Environmental Entomology,23(6): 1516-1523, 1994.
Hoshi-Sakoda, M., “Structure Activity Relationships of Enzoxazolinones with Respect to Auxin-Induced Growth and Auxin-Binding Protein”,Phytochemistry,vol. 37 No. 2, 297-300, 1994.
Hayashi et al., “6-Methoxy-2-benzoxazolinone inScoparia dulcisand its production by cultured tissues,”Phytochemistry,37(6): 1611-1614, 1994.
Leighton et al., “Substrate specificity of a glucosyltransferase and an N-hyroxylase involved in the biosynthesis of chyclic hydroxamic acids in Gramineae,”Phytochemistry,36(4): 887-892, 1994.
Mayoral et al., “A high performance liquid chromatography method for quantification of DIBOA, DIMBOA, and MBOA from aqueous extracts of corn and winter cereal plants,”Journal of Liquid Chromatography,vol. 17, No. 12, pp. 2651-2665, 1994.
Assabgui et al., “Hydroxamic acid content of maize (Zea mays) roots of 18 Ontario hybrids and prediction of antibiosis to western corn rootworm.Diabrotica virgfera virgifera Leconte(Cleoptera: Chrysomelidae),”Canadian Journal of Plant Science,73: 359-363, 1993.
Cuevas et al., “Effect of hydroxamic acids from cereals on aphid cholinesterases,”Phytochemistry,34(4): 983-985, 1993.
Frandsen et al., “Maternal transfer of the 6-MBOA chemical signal inMicrotus montanusduring gestation and lactation,”Canadian Journal of Zoology,71: 1799-1803, 1993.
Richardson et al., “Cyclic hydroxamic acid accumulation in corn seedlings exposed to reduced water potentials before, during, and after germination,”Journal of Chemical Ecology,19(8): 1613-1624, 1993;* Assabgui et al., “Hydroxamic acid content of maize roots of 18 Ontario hybrids and prediction of antibiosis to western corn rootworm,”Canada Journal of Plant Science,73: 359-363, 1993.
Bjostad, Louis B. and Hibbard, Bruce E., “6-Methoxy-2-Benzoxazolinone: a Semiochemical for Host Location by Western Corn Rootworm Larvae,”Journal of Chemical Ecology,vol. 18, No. 7, pp. 931-944, 1992.
Arnason et al., “Phototoxins in plant-insect interactions. In Herbivores, Their interactions with secondary plant metabolites,” Edited b M. Berenbaum et al., Academic Press, N.Y.;Ecological and evolutionary processes,pp. 317-341 vol. II, 2ndEd., 1992.
Blum et al., “Allelopathic activity in wheat-conventional and wheat-no-till soils: development of soil extract bioassays,”Journal of Chemical Ecology,18(12): 2191-2221, 1992.
Givovich et al., “Hydroxamic Acid Glucosides in Honeydew of Aphids Feeding on Wheat,” Journal of Chem
Forsberg Scott R.
Rosenfeld Mark J.
Seroctin Research & Technology, Inc.
Weddington Kevin E
Workman Nydegger
LandOfFree
Compounds for use in weight loss and appetite suppression in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds for use in weight loss and appetite suppression in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for use in weight loss and appetite suppression in... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4093470