Compounds for treatment or prophylaxis of cardiac disorders

Details Compounds for treatment or prophylaxis of cardiac disorders Compounds for treatment or prophylaxis of cardiac disorders

1983-05-25

1986-08-05

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560106, 560110, C07C10142, C07C10130

Patent

active

046044817

ABSTRACT:
A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.

REFERENCES:
patent: 3501769 (1970-03-01), Crowther et al.
patent: 4402974 (1983-09-01), Matier et al.
patent: 4405642 (1983-09-01), Kam et al.
Tatsuno et al., J. Med. Chem., vol. 20, 394-397 (1977).
O'Donnell et al., J. Pharm. Sci., 68, 1236-1238 (1979).

Affiliated with

Also associated with

Rating

Compounds for treatment or prophylaxis of cardiac disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds for treatment or prophylaxis of cardiac disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for treatment or prophylaxis of cardiac disorders will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-969939