Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-06-04
1999-08-17
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544324, 544325, A61K 31505, C07D40304
Patent
active
059394242
ABSTRACT:
The invention relates to 4-Amino-2-ureidopyrimidine-5-carboxamides of the formula I ##STR1## in which R.sup.1 is H or (C.sub.1 -C.sub.8)-alkyl, where one or more H can be replaced by F; R.sup.2 is selected from the group consisting of F, Cl, Br, H, -O-(C.sub.1 -C.sub.8)-alkyl, and -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; R.sup.3 is -O-(C.sub.1 -C.sub.8)-alkyl or -S-(C.sub.1 -C.sub.8)-alkyl, where the alkyl groups have one or more H replaced by F; or R.sup.2 and R.sup.3 together form -O-(C.sub.1 -C.sub.5)-alkylene-O-, where the alkylene portion has one or more H replaced by F; and their physiologically tolerable salts. The invention further provides processes for preparing the compounds of formula I. The compounds are suitable for the treatment of disorders of lipid metabolism.
REFERENCES:
patent: 5571816 (1996-11-01), Kampe et al.
Chomczynski et al., "Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction," Analytical Biochemistry, vol. 162, pp. 156-159, 1987.
Boger Hans Georg
Hoffmann Axel
Jahne Gerhard
Krass Norbert
Schafer Hans-Ludwig
Hoechst Aktiengesellschaft
Kessinger Ann M.
Raymond Richard L.
LandOfFree
Compounds for treating disorders of lipid metabolism and their p does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds for treating disorders of lipid metabolism and their p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for treating disorders of lipid metabolism and their p will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-315009