Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-04-12
2005-04-12
Priebe, Scott D. (Department: 1632)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S252300, C435S252330, C435S254110, C435S320100, C435S410000, C435S455000, C435S468000, C435S471000, C536S023200, C536S023500
Reexamination Certificate
active
06878529
ABSTRACT:
Polynucleotide and polypeptide sequences are described. The polypeptide sequences comprise one or more of: (a) a polypeptide having the deduced amino acid sequence translated from the polynucleotide sequence in SEQ ID NO: 1 or SEQ ID NO: 5 and variants, fragments, homologues, analogues and derivatives thereof; (b) a polypeptide of SEQ ID NO: 2 and variants, fragments, homologues, analogues and derivatives thereof (c) a polypeptide encoded by the cDNA of NCIMB 41110 and variants, fragments, homologues, analogues and derivatives thereof; or (d) a polypeptide which has at least 78% identity to (i) the polypeptide encoded by the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 5, (ii) the polypeptide of SEQ ID NO: 2, or (iii) the polypeptide encoded by the cDNA of NCIMB 41110. Such polypeptide sequences are, inter alia, useful in the prophylaxis and/or treatment of sexual dysfunction, in particular male erectile dysfunction (MED) or female sexual dysfunction (FSD), preferably female sexual arousal disorder (FSAD).
REFERENCES:
patent: 20020102707 (2002-08-01), Harrow et al.
patent: 1069188 (2000-01-01), None
patent: WO9953077 (1999-10-01), None
patent: WO0047750 (2000-08-01), None
Kinzler et al., “Whole genome PCR: application to the identification of sequences bound by gene regulatory proeins,” Nucl. Acids Res. 17 (10): 3645-3653, 1989.*
GenBank Acc. No. AW372628, US National Library of Medicine, Bethesda, MD, Feb. 4, 2000, accessed by PTO on Oct. 24, 2003.*
GenBank Acc. No. AW955378, US National Library of Medicine, Bethesda, MD, Jun. 1, 2000, accessed by PTO on Oct. 24, 2003.*
GenBank Acc. No. AI422225, US National Library of Medicine, Bethesda, MD, Mar. 30, 1999, accessed by PTO on Oct. 24, 2003.*
GenBank Acc. No. R54681, US National Library of Medicine, Bethesda, MD, May 22, 1995, accessed by PTO on Oct. 24, 2003.*
Rudinger, J., “Characteristics of the amino acids components of a peptide hormone sequence,” in Peptide Hormones, Parsons (ed.), University Park Press: Baltimore, MD, pp. 1-7, 1976.*
GenBank Acc. No. AF067196, US National Library of Medicine, Bethesda, MD, Jul. 1, 1998, accessed by PTO on Oct. 29, 2003.*
Kennell, D.E. “Principles and practices of nucleic acid hybridization,” Progr. Nucl. Acid Res. Mol. Biol. 11: 259-301, 1971.*
Ngo et al., “Computational complexity, protein structure prediction, and the Levinthal paradox,” in The Protein Folding Problem and Tertiary Structure Prediction, Merz et al. (eds.), Birkhauser Boston: Boston, MA, pp. 433 and 492-495, 1994.*
Ikeda, K., et al.The Journal of Biological Chemistry, vol. 274, No. 5: pp. 32469-32477, 1999.
Ghaddar, G., et al.,Biochem. J., vol. 347: pp. 419-429, 2000.
Harrow Ian Dennis
Phillips Stephen Charles
Stacey Peter
Walsh Roderick Thomas
Wayman Christopher Peter
Benson Gregg C.
Martin Deborah A.
Pfizer Inc.
Priebe Scott D.
Richardson Peter C.
LandOfFree
Compounds for the treatment of sexual dysfunction does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds for the treatment of sexual dysfunction, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for the treatment of sexual dysfunction will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3406551