Compounds for the treatment of hepatoma

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549392, A61K 3135

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active

057418136

ABSTRACT:
Compounds of general Formula I in which the substituents of R.sub.1 -R.sub.7 are hydrogen, hydroxy group, C.sub.1-6 alkyl group, C.sub.1-6 alkoxy group, or epoxypropoxy, but at the most, six of the substituents can simultaneously be hydrogen, methoxy group, or hydroxy group, or epoxypropoxy group for activity against hepatoma. There are also described processes for the preparation of the novel compounds and useful intermediates. Substitute benzophenones are described.

REFERENCES:
patent: 3912733 (1975-10-01), Santilli et al.
patent: 5495005 (1996-02-01), Lin et al.
patent: 5516794 (1996-05-01), Da Re et al.
Lion et al., J. Pharm. Pharmacol. 45, 791-794 (Sep. 1993).

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