Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1996-05-15
1998-09-22
Minnifield, Nita
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
4241931, 4241841, 4242801, 514 2, 514 12, 540575, A61K 39385, A61K 3939, A61K 3800, C07D24308
Patent
active
058111000
ABSTRACT:
A compound for protecting a vertebrate against infection by helminths comprising hyaluronidase covalently coupled to an immunostimulating carrier, in preferred form, the immunostimulating carrier to which the hyaluronidase is covalently coupled comprising a copolymer of ethylenepiperazine N-oxide and N-ethylacetylethylenepiperazinium bromide (hereafter referred to as "SYNPOL"), and a process for protecting a vertebrate against infection by helminths comprising administration to the vertebrate of a therapeutically effective amount of a compound comprising hyaluronidase covalently coupled to an immunostimulating carrier, preferably SYNPOL, in preferred form, the compound being administered to the vertebrate in the form of a vaccine.
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Ataullakhanov Ravshan I.
Daugalieva Emma K.
Khaitov Rakhim M.
Nekrasov Arkady V.
Petrov Rem V.
Minnifield Nita
Petrovax, Inc.
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