Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-05-29
2007-05-29
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S506000, C514S528000, C548S479000, C560S160000
Reexamination Certificate
active
10618578
ABSTRACT:
The invention relates to compounds for the modulation of the glycolysis enzyme complex and of the transaminase complex, pharmaceutical compositions containing such compounds as well as uses of such compounds for preparing pharmaceutical compositions for treating various diseases.
REFERENCES:
patent: 198 57009 (2000-06-01), None
patent: WO 99/54286 (1999-10-01), None
Eigenbrodt, E.; Gerbracht, U; Mazurek, S.; Presek, P.; Frus, R. “Carbohydrate Metabolism and Neoplasia: New Perspectives for Diagnosis and Therapy”. Biochemical and Molecular Aspects of Selected Cancers. Chapter 10. vol. 2. pp. 311-385. 1994.
Kauppinen, Risto A.; Sihra, Talvinder S.; Nicholls, David G. “Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates”. Elsevier Science Publishers (Biomedical Division). vol. 930. 1987. pp. 173-178.
Tomasiak, Marian. “The Importance of Aspartate Aminotransferase for Platelet Aggregation”. Haematologia. vol. 19. No. 2. 1986. pp. 101-112.
Tomasiak, Marian, “Importance of the malate-aspartate shuttle for the reoxidation of glycolytically produced nadh and for cell aggregation in procine blood platelets”. Aeta Biochemica Polonila. vol. 34. No. 3. 1987. pp. 269-284.
Eigenbrodt Erich
Mazurek Sybille
Scheefers Hans
Mayer & Williams PC
Park, Esq. Keum J.
Sackey Ebenezer
Saeed Kamal A.
ScheBo Biotech AG
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