Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-02
2007-10-02
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S288000
Reexamination Certificate
active
11440994
ABSTRACT:
There are provided novel compounds of formula (I)wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory diseases, pain and CNS diseases.
REFERENCES:
patent: 0 262 870 (1988-04-01), None
patent: 1264340 (1972-02-01), None
patent: WO94/02448 (1994-02-01), None
patent: WO97/17325 (1997-05-01), None
patent: WO 00/23420 (2000-04-01), None
patent: WO 01/36413 (2001-05-01), None
patent: WO 02/06276 (2002-01-01), None
Alderton et al. Biochem. J. 2001, 357, 593-615.
Kubes et al. The American Journal of Medicine Aug. 1, 2000.
Thomsen et al. Annals New York Academy of Sciences 1997, 835, 363-372.
Kmonicek et al., STN International, File HCAPLUS, No. 1992:105741, Doc. 116:105741.
Vercouillie et al., Journal of Labelled Compounds and Radiopharmaceuticals, 2001, vol. 44, 113-120.
Glinka, STN International, File CAPLUS, No. 1984: 191848, Doc. 100:161848.
Ol, et al. STN International, File CAPLUS, No. 2000:277959, Doc. 132:321662.
Oya et al., Nuclear Medicine & Biology, 2000, vol. 27, 249-254.
Tarkiainen et al., Journal of Labelled Compounds and Radiopharmaceuticals, 2001, vol. 44, 113-120.
Emond et al., J. Med. Chem., 2002, vol. 45, 1253-1258.
Connolly Stephen
Ernst Glen
Anderson Rebecca
AstraZeneca AB
Nolan Jason M
White & Case LLP
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