Compounds for nonsense suppression, and methods for their use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S131000

Reexamination Certificate

active

07902235

ABSTRACT:
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

REFERENCES:
patent: WO 97/44333 (1997-11-01), None
patent: WO 2004/009558 (2004-01-01), None
patent: WO 2004/009610 (2004-01-01), None
STN Search Report Accession No. 1997:776160.
Han (Advances in Characterization of Pharmaceutical Hydrates. Trends in Bio/Pharmaceutical Industry, pp. 25-29. Mar. 2006).
Vippagunta et al (Adv Drug Deliv Rev 48:3-26, 2001).
International Search Report for PCT/US2005/037052, mailed Feb. 1, 2006.

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