Compounds for molecular separations

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

204451, 204455, 204601, 204655, G01N 2726, G01N 27447

Patent

active

060745428

ABSTRACT:
The present invention describes a method and apparatus utilizing a capillary coating of linear and crosslinked polymers and copolymers of acrylamidomonomers or methacrylamides bearing two hydroxyethyl residues. The method and apparatus employ this coating to maintain coating integrity and suppress electroosmotic flow under basic conditions in capillary electrophoresis.

REFERENCES:
patent: 5089111 (1992-02-01), Zhu et al.
patent: 5143753 (1992-09-01), Novotny et al.
patent: 5470916 (1995-11-01), Righetti et al.
patent: 5567292 (1996-10-01), Madabhushi et al.
S. Hjerten, "High Performance Electrophoresis: Elimination of Electro-endosmosis and Solute Adsorption" Journal of Chromatography vol. 347 (1985) 191-198, no month available.
N. Iki and E. Yeung, "Non-bonded poly(ethylene oxide) polymer-coated column for protein separation by capillary electrophoresis", Journal of Chromatography A, 731 No month available (1996), pp. 273-282.
M. Huang et al., "Hydrolytically stable cellulose-derivative coatings for capillary electrophoresis of peptides, proteins and glycoconjugates", Electrophoresis 16 No month available (1995), pp. 396-401.
A. Cifuentes et al., "Selectivity change in the separation of porteins and peptides by capillary electrophoresis using high-molecular-mass polyethyleneimide", Journal of Chromatography B, 681 No month available (1996), pp. 21-27.
S. Hjerten, "High-Performance electrophoresis; Elimination of of electroendosmosis and Solute Adsorption", Journal of Chromagraphy, 347 No month available (1985), pp. 191-198.
M. Huang et al., "Evaluation of Surface-bonded Polyethylene Glycol and Polyethylene Imine in Capillary Electrophoresis", J. Microcol. Sep. 4 (1992), pp. 135-143.
M. Chiari et al., "Capillary electrophoretic separation of proteins using stable, hydrophilic poly(acryloylaminoethoxyethanol)-coated columns", Journal of Chromatography A, 717 No month available (1995), pp. 1-13.
M. Chiari et al., "Synthesis and Characterization of Capillary Columns Coated with Glycoside-Bearing Polymer", Analytical Cheminstry, vol. 68, No. 17, Sep. 1, 1996, pp. 2731-2736.
E. Simo-Alfonso et al., "Novel acrylamido monomers with higher hydrophilicity and improved hydrolytic stability: I. Synthetic route and product characterization", Electrophoresis 17, No month available 1996.
S. Hjerten, "A new type of pH- and detergent-stable coating for elimination of electroendosmosis and adsorption in (capillary) electrophoresis", Electrophoresis 14, No month available 1993, pp. 390-395.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compounds for molecular separations does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds for molecular separations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds for molecular separations will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2065673

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.