Compounds for inhibiting immune response

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544225, 546 2, A61K 3324, C07F 100

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active

055126871

ABSTRACT:
Novel ruthenium complexes for use as immunosuppressive agents to prevent or significantly reduce graft rejection in organ and bone marrow transplantation are described. The ruthenium complexes can also be used as an immunosuppressant drug for T-lymphocyte mediated autoimmune diseases, such as diabetes, and may be useful in alleviating psoriasis and contact dermatitis.

REFERENCES:
patent: 4549018 (1985-10-01), Siedle
patent: 4843069 (1989-06-01), Keller et al.

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