Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Reexamination Certificate
2006-05-02
2006-05-02
Leffers, Gerry (Department: 1636)
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
C435S320100, C435S007100, C435S006120, C536S023100
Reexamination Certificate
active
07037706
ABSTRACT:
Replicable genetic packages and collections thereof that display various compounds are provided. In some instances, the replicable genetic packages include nucleic acid tags that serve to record a characteristic of the compound or compounds that are attached to the replicable genetic package. The invention further provides a number of different methods for using the replicable genetic packages to screen a library of compounds for a desired biological activity.
REFERENCES:
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5514548 (1996-05-01), Krebber et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5639603 (1997-06-01), Dower et al.
patent: 5723598 (1998-03-01), Lerner et al.
patent: 5766905 (1998-06-01), Studier et al.
patent: 5837500 (1998-11-01), Ladner et al.
patent: 5958703 (1999-09-01), Dower et al.
patent: 6027890 (2000-02-01), Ness et al.
patent: 6057098 (2000-05-01), Buechler et al.
patent: 6309842 (2001-10-01), Dower et al.
patent: 6777239 (2004-08-01), Dower et al.
patent: WO 93/11236 (1993-06-01), None
patent: WO 97/10507 (1997-03-01), None
patent: WO 98/51325 (1998-11-01), None
patent: WO 98/51825 (1998-11-01), None
patent: WO 01/05950 (2001-01-01), None
Brenner, Sydney and Richard A. Lerner; Encoded combinatorial chemistry; Proc. Natl. Acad. Sci. USA; Jun. 1992; pp. 5381-5383; vol. 89.
Ellman, Jonathan A. and Mark A. Gallop; Combinatorial chemistry—Editorial overview; Current Opinion in Chemical Biology; 1998; pp. 317-319; vol. 2.
Armstrong, et al., “Orientation of the Virion During Assembly and Disassembly,”IRL Press Limited,1641-1646 (1983).
Chang, et al., “Subtiligase: A Tool for Semisynthesis of Proteins,”Proc. Natl. Acad. Sci. USA91:12544-12548 (1994).
Cwirla, et al., “Peptides on Phage: A Vast Library of Peptides for Identifying Ligands,”Nat. Acad. Sci. USA87:6378-6382 (1990).
Devlin, et al., “Random Peptide Libraries: A Source of Specific Protein Binding Molecules,”Science249:404-406 (1990).
Dwyer, et al., “Biosynthetic Phage Display: A Novel Protein Engineering Tool Combining Chemical and Genetic Diversity,”Chemistry&Biology7(4):263-274 (2000).
Nakashima, et al., “Chemical Modification and Molecular Orientation of the B Protein in the Filamentous Bacterial Virus Pf1,”J. Mol. Biol.138:493-501 (1980).
Sandman, et al., “Phage Display of Selenopeptides,”J. Am. Chem. Soc.122:960-961 (2000).
Scott, et al., “Searching for Peptide Ligands with an Epitope Library,”Science249:386-390 (1990).
Crameri R. et al. “Display of Biologically Active Proteins on the Surface of Filamentous Phages: A cDNA Cloning System for Selection of Functional Gene Products Linked to the Genetic Information Responsible for their Production”Gene, 1993, pp. 69-75, vol. 137, Elsevier Science, NL.
Dente, Luciana et al. “Modified Phage Peptide Libraries as a Tool to Study Specificity of Phophorylation and Recognition of Tyrosine Containing Peptides”J. Molecular Biology, Jul. 27, 1997, pp. 694-703, vol. 269, No. 5, England.
Maclean, D. et al. “Encoded combinatorial chemistry: synthesis and screening of a library of highly functionalized pyrrolidines.”Proceedings of the National Academy of Sciences of the United States of America,Apr. 1, 1997, pp. 2805-2810, vol. 94, No. 7, USA.
Woiwode, Thomas F. et al. “Synthetic compound libraries displayed on the surface of encoded bacteriophage.”Chemistry and Biology,Sep. 2003, pp. 847-858, vol. 10, No. 9, England.
Barrett Ronald W.
Cwirla Steven E.
Dower William J.
Gallop Mark
Woiwode Thomas F.
Leffers Gerry
Townsend and Townsend / and Crew LLP
Xenoport, Inc.
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