Compounds containing phenyl linked to aryl or heteroaryl by an a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514277, 514679, 514685, 514706, 514712, 514713, 514717, 514718, 514719, 514720, 514721, 546314, 546339, 568 20, 568 39, 568 42, 568 45, 568 49, 568 51, 568325, 568331, 568631, 568644, 568646, A61K 3144, C07D21302

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active

056796960

ABSTRACT:
This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical compositions containing these compounds. Furthermore, this invention is directed to the pharmaceutical use of the compounds for inhibiting cyclic AMP phosphodiesterase.

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