Compounds containing phenyl linked to aryl or heteroaryl by an a

Details Compounds containing phenyl linked to aryl or heteroaryl by an a Compounds containing phenyl linked to aryl or heteroaryl by an a

1995-06-07

1997-12-16

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562426, 562432, 562465, 562470, 562471, C07D33302, C07C 1310, C07C 320

Patent

active

056987110

ABSTRACT:
This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical compositions containing these compounds. Furthermore, this invention is directed to the pharmaceutical use of the compounds for inhibiting cyclic AMP phosphodiesterase.

REFERENCES:
patent: 4971959 (1990-11-01), Hawkins
patent: 5274002 (1993-12-01), Hawkins
patent: 5340827 (1994-08-01), Beeley et al.
patent: 5563143 (1996-10-01), Cohan et al.

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