Compounds containing a fused multiple ring lactam

Details Compounds containing a fused multiple ring lactam Compounds containing a fused multiple ring lactam

1993-11-18

1996-06-11

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

514214, C07D47104, A61K 3764

Patent

active

055257232

ABSTRACT:
Compounds of the formula ##STR1## wherein A is ##STR2## are useful as ACE and NEP inhibitors and those wherein A is ##STR3## are useful as ACE inhibitors. Methods of preparation and intermediates are also disclosed.

REFERENCES:
patent: 4105776 (1978-08-01), Ondetti et al.
patent: 4337201 (1982-06-01), Petrillo
patent: 4374829 (1983-02-01), Harris et al.
patent: 4432971 (1984-02-01), Karanewsky et al.
patent: 4432972 (1984-02-01), Karanewsky et al.
patent: 4460579 (1984-07-01), Karanewsky
patent: 4584294 (1986-04-01), Ruyle
patent: 4711884 (1987-12-01), Karanewsky
patent: 4749688 (1988-06-01), Haslanger et al.
patent: 4801609 (1989-01-01), Haslanger et al.
patent: 4824832 (1989-04-01), Flynn et al.
patent: 4873235 (1989-10-01), Parsons et al.
patent: 4879309 (1989-11-01), Doll et al.
patent: 4973585 (1990-11-01), Flynn et al.
patent: 5061710 (1991-10-01), Haslanger et al.
patent: 5075302 (1991-12-01), Neustadt
patent: 5225401 (1993-07-01), Seymour
patent: 5362727 (1994-11-01), Robl
patent: 5366973 (1994-11-01), Flynn et al.
Flynn et al., Tetrahydron Letters, vol. 31, pp. 815-818 (1990).
Flynn et al., J. Med. Chem., vol. 36, pp. 2420-2433 (1993).
Chackalamannil et al., Bioorganic & Medicinal Chemistry Letters, vol. 2, pp. 1003-1006 (1992).

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