Compounds compositions and methods for treating influenza

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514253, 514254, 544238, 544240, A61K 3150, A61K 31495, C07D40100, C07D23702

Patent

active

058212434

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sub.1 represents a lower alkyl (C.sub.1 --C.sub.6) substituent which may be straight or branched; R.sub.2 represents an aryl substituent of the formula: ##STR2## and Q, V, W, X, Y and Z are as set forth in the accompanying specification. These compounds are useful in prophylaxis and treatment of influenza virus infection.

REFERENCES:
patent: 3152180 (1964-10-01), Haaf
patent: 3352912 (1967-11-01), Prichard
patent: 3483254 (1969-12-01), Shen et al.
patent: 3496228 (1970-02-01), Hoover
patent: 3534084 (1970-10-01), Narayanan et al.
patent: 3538160 (1970-11-01), Dunn et al.
patent: 3592934 (1971-07-01), Prichard
H. Fraenkel-Conrat and A. Steinschneider, "Stepwise Degradation of RNA: Periodate Followed by Aniline Cleavage," Methods in Enzymology, 12B: 243-246 (1967).
S.J. Plotch, M. Bouloy and R.M. Krug, "Transfer of 5'-Terminal Cap of Globin mRNA to Influenza Viral Complementary RNA during Transcription in Vitro," Proc. Natl. Acad. Sci. USA, 76: 1618-1622 (1979).
R. Pauwels, J. Balzarini, M. Baba, R. Snoeck, D. Schols, P. Herdewijn, J. Desmyter and E. DeClerq, "Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds", J. Virol. Methods, 20: 309-321 (1988).
G.A. Russell and P. Bruni, "Aliphatic Semidiones--XI: Radical Anions Derived by Reduction of 1-Phenyl-3-methyl-2-pyrazoline-4,5-dione, 1,2,-diphenylpyrazolidene-3,4,5-trione and 1,1'-Diphenyl-3,3'-di-methyl-4,4'-bis-2-pyrazoline-5-5'-dione (Pyrazole-blue)", Tetrahedron, 26: 3449-3456 (1970).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compounds compositions and methods for treating influenza does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds compositions and methods for treating influenza, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds compositions and methods for treating influenza will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-313402

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.