Compounds as pharmaceutical agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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Details

C546S139000, C546S275700

Reexamination Certificate

active

07405299

ABSTRACT:
The current invention relates to compounds of the formula: (Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.

REFERENCES:
patent: 7087626 (2006-08-01), Beight et al.
patent: 2006/0040983 (2006-02-01), Beight et al.
patent: 2006/0079680 (2006-04-01), Sawyer
patent: WO 02 062787 (2002-08-01), None
patent: WO 02 062794 (2002-08-01), None
patent: WO 02 066462 (2002-08-01), None
patent: 2002094833 (2002-11-01), None
patent: WO 02 094833 (2002-11-01), None
Freshney (Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, pp. 1-6.
Dermer (Bio/Technology, 1994, 12:320).

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