Compounds and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S122000

Reexamination Certificate

active

07005434

ABSTRACT:
The present invention relates to novel compounds and the treatment of mammalian diseases in which inappropriate, excessive or undesirable angiogenesis has occurred and/or where excessive Tie2 receptor activity has occurred.

REFERENCES:
patent: 5945431 (1999-08-01), Jin et al.
patent: 6025489 (2000-02-01), Davey et al.
patent: WO 96/15128 (1996-05-01), None
patent: WO 97/34894 (1997-09-01), None
patent: WO 99/09030 (1999-02-01), None
patent: WO 99/29318 (1999-06-01), None
patent: WO 96/61444 (1999-12-01), None
Thompson, A.M., et al., “3-(3,5-Dimethoxyphenyl)-1,6-Naptthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosone kinase”, (2000), J. Med. Chem.,vol. 43, pp. 4200-4211.

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