Compounds and use thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S255050, C514S255060, C514S252100, C544S343000

Reexamination Certificate

active

08076341

ABSTRACT:
A compound of formula (I) wherein R1is selected from H, F, Cl, Br, CF3, C1-C6alkoxy and OH; R2is selected from H and C1-C6alkyl; n is 1-12; m is O or 1; Y is selected from CH2, NR3, (NR3R4)+X, O and S; R3and R4are independently selected from H and C1-C4alkyl; and X″ is selected from phannaceutically acceptable anions. A method of preparing the compound, its use as a pharmaceutical, and a method of treatment.

REFERENCES:
patent: 0 238 459 (1987-09-01), None
Harmenberg, J., et al. “Antiherpesvirus Activity and Mechanism of Action of Indolo-(2,3-b) Quinoxaline and Analogs.”Antimicrobial Agents and Chemotherapy(1988) vol. 32, No. 11, pp. 1720-1724.
Collino, F., et al. “Basi di Mannich A Struttura Dipiperidnica Dotate di Attivita' Farmacologica.”Bolletino Chimico Farmaceutico(1982) vol. 121, No. 8, pp. 408-421.
Patani, George A., et al. Biososterism: A Rational Approach in Drug Design. Chem. Rev. 1996, 96, pp. 3147-3176. Dec. 19, 1996.

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