Compounds and their use as glycine transport inhibitors

Details Compounds and their use as glycine transport inhibitors Compounds and their use as glycine transport inhibitors

2005-07-26

2005-07-26

Dentz, Bernard (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S469000, C514S517000, C514S530000, C514S563000, C514S620000, C549S006000, C549S058000, C549S220000, C549S345000, C549S467000, C558S166000, C562S048000, C562S104000, C562S428000, C562S443000, C562S444000, C564S164000, C560S038000

Reexamination Certificate

active

06921774

ABSTRACT:
The invention provides novel compounds of the formula I below:wherein the meaning of each substituent is defined in the application. The compounds are useful as inhibitors of the glycine transporter and useful in the treatment of diseases responsive to the inhibition of the glycine transporter. The invention provides a pharmaceutical composition comprising a compound of Formula I as defined above and the use of compounds as above for the manufacture of medicaments for treatment of diseases responsive to ligands of the glycine transporter.

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