Compounds and methods for treatment of thrombosis

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S350000, C530S380000, C530S381000, C530S412000

Reexamination Certificate

active

10817248

ABSTRACT:
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.

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Information, Applicant's Statement, Jun. 2006.

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