Compounds and methods for treating diabetic complications

Details Compounds and methods for treating diabetic complications Compounds and methods for treating diabetic complications

1977-12-29

1980-04-15

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 94, A61K 3140, C07D20960

Patent

active

041984145

ABSTRACT:
Novel4-H-pyrrolo[3,2,1-ij]quinolin-1,2-diones having the formula ##STR1## wherein R.sup.1 is hydrogen or methyl and R.sup.2 is methyl or phenyl are disclosed. The compounds are useful as inhibitors of aldose reductase.

REFERENCES:
patent: 3917838 (1975-11-01), Bass et al.
patent: 4015005 (1977-03-01), Hardtmann
Dvornik et al., "Science", 182, pp. 1146 & 1147 (1973).

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