Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants
Reexamination Certificate
1999-02-23
2001-05-01
Levy, Neil S. (Department: 1616)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Biocides; animal or insect repellents or attractants
C424S405000, C424S406000, C424S407000, C424S409000, C424S410000, C424S417000, C514S024000, C514S025000, C514S042000, C514S053000, C514S054000, C514S061000, C514S063000
Reexamination Certificate
active
06224891
ABSTRACT:
BACKGROUND OF THE INVENTION
Field of the Invention
This invention relates to the treatment of diarrhea and related conditions caused by pathogenic
E. coli
infection. More specifically, this invention is drawn to the unexpected discovery that by administering a composition which binds and removes the shiga like toxins (SLT) produced by pathogenic
E. coli
whenever an antibiotic is administered, improved treatment is provided. Novel compositions containing both antibiotic and toxin binding composition and methods of treatment which use simultaneous administration of toxin binding composition whenever antibiotic is administered are provided. These compositions and methods kill the enteric
E. coli
organisms which produce the conditions and neutralize the SLT produced by the organisms and/or released from the organisms when they are killed. Thus, these compositions and methods are better able to ameliorate the symptoms of the infection and inhibit progression of this infection into hemolytic uremic syndrome (HUS) than conventional treatment.
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The disclosure of the above publications, patents and patent application are herein incorporated by reference in their entirety to the same extent as if the language of each individual publi
Armstrong Glen D.
Rafter David John
Ratcliffe Robert Murray
Thompson Bradley G.
Burns, Doane, Swecker & Mathis, LLP.
Levy Neil S.
Synsorb Biotech Inc.
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