Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-05-30
1999-03-02
Housel, James C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4241841, 4242341, 4242651, 4242691, 536 231, 536 237, 530350, A61K 3900, A61K 3902, C07K 100, C07H 2102
Patent
active
058769668
ABSTRACT:
Compounds and methods for stimulating and enhancing immune responses and for evaluating patient immune responses are disclosed. Disclosed compounds include polypeptides that contain at least a biologically active portion of a Leishmania braziliensis homolog of the eukaryotic initiation factor 4A, or a variant thereof. Such compounds are useful for stimulating a Th1 immune response and IL-12 production in patients, as well as in isolated cells and cell cultures. The polypeptides of this invention are further useful for the evaluation and treatment of patients, who may be afflicted with leishmaniasis or other disorders.
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Corixa Corporation
Housel James C.
Ryan V.
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