Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Thymopoietin or lipotropin; related peptides
Reexamination Certificate
2005-03-01
2005-03-01
Tate, Christopher (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Thymopoietin or lipotropin; related peptides
C530S300000, C435S069200, C514S255050
Reexamination Certificate
active
06861504
ABSTRACT:
The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.
REFERENCES:
patent: 5595885 (1997-01-01), Stetler-Stevenson
patent: 5691382 (1997-11-01), Crimmin et al.
patent: 6232315 (2001-05-01), Shafer
Millennium product sheet- Intergrilin ® (eptifibatide).*
Calbiochem product sheet- inhibitors of MMPs- TIMP-2, human, recombinant.*
“MMP Inhibitors and TAPI Quick Reference from Peptides International” accessed at: www.pepnet.com/tapi.html on Sep. 11, 2002.
“Matrix Metalloproteinases (MMPs)>> Inhibitors of MMPs.” Catalog Nos. 324385, 364205, and 444274 accessed at: www.calbiochem.com/Products/ on Sep. 11, 2002.
INTEGRILLIN® product description accessed at: www.millennium.com/integrilin.html on Sep. 11, 2002.
Andre Patrick
Phillips David
Wagner Denisa D.
CBR, Inc.
Fish & Richardson P.C.
Millenium Pharmaceuticals, Inc.
Tate Christopher
Teller Roy
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