Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-14
2010-02-23
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S152000
Reexamination Certificate
active
07666886
ABSTRACT:
The invention is in general directed to compounds and methods for diagnosing, preventing or alleviating the symptoms of amyloid-associated diseases, for example, neuronal diseases, such as, for example, Alzheimer's disease, methods of screening for compounds useful in preventing or alleviating the symptoms of amyloid-associated diseases, methods of diagnostic imaging of A-beta fibrils, and compounds and methods useful for studying normal or disease-associated cellular mechanisms relating to amyloid proteins.
REFERENCES:
patent: 6479528 (2002-11-01), Kuret et al.
patent: 6696039 (2004-02-01), Kung et al.
Mateeva et al. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry.
Blower, P. Annual Report on the Progress of Chemistry, Section A, 1999, 95, 631-55.
Mashraqui et al. Indian Journal of Chemistry, 2006, 45B (3), 815-19.
Inbar et al. ChemBioChem, 2006, 7(10), 1563-66, available online Jul. 6, 2006.
Ishikawa, K. et al., “Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies,” Journal of General Virology (2004), 85:1785-90, Jun. 2004.
Levine, H., “Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: detection of amyloid aggregation in solution,” Protein Science (1993), 2:404-10, Cambridge University Press, USA, Mar. 1993.
Lockhart, A. et al., “Evidence for the presence of three distinct binding sites for the Thioflavin T class of Alzheimer's disease PET imaging agents on β-amyloid peptide fibrils*,” The Journal of Biological Chemistry, 280(9):7677-84, USA, Mar. 4, 2005.
Yan, S. et al., “Amyloid-β peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease,” Proc. Natl. Acad. Sci. USA, 94:5296-301, May 1997.
Inbar Petra
Yang Jerry
Jarrell Noble
The Regents of the University of California
Townsend and Townsend / and Crew LLP
Wilson James O
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