Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-09-15
1999-08-24
Arthur, Lisa B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
514 14, 530300, 530326, G01N 3353, A61K 3800, C07K 200, C07K 500
Patent
active
059424036
ABSTRACT:
Compounds and methods for diagnosing Trypanosoma cruzi infection, or for screening for T. cruzi or Leishmania infection, are disclosed. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more antigenic epitopes of T. cruzi proteins. The compounds are useful in a variety of immunoassays for detecting T. cruzi infection. The polypeptide compounds are further useful in vaccines and pharmaceutical compositions for preventing Chagas' disease in individuals exposed to T. cruzi.
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Houghton Raymond
Reed Steven G.
Skeiky Yasir A. W.
Arthur Lisa B.
Corixa Corporation
Souaya Jehanne
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