Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1997-04-15
2000-04-25
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
530350, 4241851, 4241911, 4241921, 4241931, A61K 39002
Patent
active
060541350
ABSTRACT:
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays for detecting T. cruzi infection. The polypeptide compounds are further useful in vaccines and pharmaceutical compositions for inducing protective immunity against Chagas' disease in individuals exposed to T. cruzi.
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Houghton Raymond L.
Lodes Michael J.
Reed Steven G.
Skeiky Yasir A. W.
Corixa
Graser Jennifer
Housel James C.
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