Compounds and methods for promoting smoking cessation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C424S001370, C546S276700

Reexamination Certificate

active

07615567

ABSTRACT:
Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.

REFERENCES:
patent: 3555154 (1971-01-01), Enkoji et al.
patent: 3734851 (1973-05-01), Matsumura
patent: 4242460 (1980-12-01), Chick et al.
patent: 4354933 (1982-10-01), Lester
patent: 4539143 (1985-09-01), Boden et al.
patent: 4568538 (1986-02-01), Boden et al.
patent: 4587981 (1986-05-01), Boden et al.
patent: 4677207 (1987-06-01), Boden et al.
patent: 4973493 (1990-11-01), Guire
patent: 5002582 (1991-03-01), Guire et al.
patent: 5128118 (1992-07-01), Carroll et al.
patent: 5141959 (1992-08-01), Carroll et al.
patent: 5298499 (1994-03-01), Carroll et al.
patent: 5360790 (1994-11-01), Humes
patent: 5380848 (1995-01-01), Kuhar et al.
patent: 5413779 (1995-05-01), Kuhar et al.
patent: 5414075 (1995-05-01), Swan et al.
patent: 5429938 (1995-07-01), Humes
patent: 5437994 (1995-08-01), Emerson et al.
patent: 5459069 (1995-10-01), Palsson et al.
patent: 5496953 (1996-03-01), Kuhar et al.
patent: 5499976 (1996-03-01), Dalton
patent: 5516680 (1996-05-01), Naughton et al.
patent: 5549674 (1996-08-01), Humes et al.
patent: 5550050 (1996-08-01), Holland et al.
patent: 5565573 (1996-10-01), Larock
patent: 5580697 (1996-12-01), Keana et al.
patent: 5605822 (1997-02-01), Emerson et al.
patent: 5639275 (1997-06-01), Baetge et al.
patent: 5653975 (1997-08-01), Baetge et al.
patent: 5656481 (1997-08-01), Baetge et al.
patent: 5661133 (1997-08-01), Leiden et al.
patent: 5676943 (1997-10-01), Baetge et al.
patent: 5686289 (1997-11-01), Humes et al.
patent: 5733727 (1998-03-01), Field
patent: 5736123 (1998-04-01), Carroll
patent: 5763266 (1998-06-01), Palsson et al.
patent: 5773286 (1998-06-01), Dionne et al.
patent: 5795790 (1998-08-01), Schinstine et al.
patent: 5817679 (1998-10-01), Shen et al.
patent: 5831095 (1998-11-01), Gonzalez et al.
patent: 5833978 (1998-11-01), Tremblay
patent: 5843781 (1998-12-01), Ballermann et al.
patent: 5858653 (1999-01-01), Duran et al.
patent: 5906817 (1999-05-01), Moullier et al.
patent: 5919449 (1999-07-01), Dinsmore
patent: 5935953 (1999-08-01), Kuhar et al.
patent: 5965125 (1999-10-01), Mineau-Hanschke
patent: 6060270 (2000-05-01), Humes
patent: 6110209 (2000-08-01), Stone
patent: 6123917 (2000-09-01), Carroll
patent: 6150164 (2000-11-01), Humes
patent: 6156304 (2000-12-01), Glorioso et al.
patent: 6177451 (2001-01-01), Qian et al.
patent: 6329520 (2001-12-01), Carroll et al.
patent: 6358492 (2002-03-01), Kuhar et al.
patent: 6416735 (2002-07-01), Carroll et al.
patent: 6479509 (2002-11-01), Carroll
patent: 6531481 (2003-03-01), Carroll et al.
patent: 6531483 (2003-03-01), Kuhar et al.
patent: 6538010 (2003-03-01), Carroll
patent: 6552032 (2003-04-01), Carroll et al.
patent: 6559159 (2003-05-01), Carroll et al.
patent: 6593348 (2003-07-01), Carroll et al.
patent: 6706880 (2004-03-01), Carroll et al.
patent: 6900228 (2005-05-01), Carroll et al.
patent: 2002/0132828 (2002-09-01), Carroll et al.
patent: 2002/0188003 (2002-12-01), Kuhar et al.
patent: 2003/0158415 (2003-08-01), Carroll et al.
patent: 2003/0176434 (2003-09-01), Carroll
patent: 2003/0203934 (2003-10-01), Kuhar et al.
patent: 2004/0146518 (2004-07-01), Carroll et al.
patent: 2005/0197360 (2005-09-01), Kuhar et al.
patent: 0 154 844 (1985-09-01), None
patent: 0 955 301 (1999-11-01), None
patent: 1 479 002 (1974-06-01), None
patent: 60-208961 (1985-10-01), None
patent: 07-61940 (1995-03-01), None
patent: 11-501282 (1999-02-01), None
patent: 11-322751 (1999-11-01), None
patent: WO 89/01967 (1989-03-01), None
patent: W0 91/00119 (1991-01-01), None
patent: WO 92/07615 (1992-05-01), None
patent: WO 93/17696 (1993-09-01), None
patent: WO 95/07078 (1995-03-01), None
patent: WO 96/06093 (1996-02-01), None
patent: WO 01/44243 (2001-06-01), None
W. Glassco, et al., “Comparative Sar Studies of N-Substituted Nornicotines and N-Substituted Norbridged Nicotines”, Problems of Drug Dependence, 1994: Proceedings of the 56thAnnual Scientific Meeting, The College on Problems of Drug Dependence, Inc., vol. II: Abstracts, p. 190.
M. Damaj, et al., “Pharmacological Characterization of Nicotine's Interaction with Cocaine and Cocaine Analogs1”, The Journal of Pharmacology and Experimental Therapeutics, vol. 289, No. 3, 1999, pp. 1229-1236.
E. albertini, et al., “Enantioselective Approach to 7-Azabicyclo[2.2.1]heptane Ring systems Using D-(−)-Quinic Acid as the Chiral Educt: Application to the Formal Synthesis of (+)-Epibatidine”, Tetrahedron Letters, vol. 38, No. 4, 1997, pp. 681-684.
G. Lloyd, et al., “Neuronal Nicotinic Acetylcholine Receptors as Novel Drug Targets”, The Journal of Pharmacology and Experimental Therapeutics, vol. 292, No. 2, 2000, pp. 461-467.
D. Bai, et al., “Epibatidine”, Drugs of the Future, vol. 22, No. 11, 1997, pp. 1210-1220.
S. Singh, et al., “Efficient Synthesis of (+)-N-BOC-exo-2-(methoxycarbony1)-7-Azabicyclo[2.2.1]heptane, A Versatile Intermediate for the Synthesis of Epibatidine and Epiboxidine”, Tetrahedron Letters. vol. 38, No. 39, 1997, pp. 6829-6830.
M. Davila-Garcia, et al., “[125]IPH, An Epibatidine Analog, Binds with High Affinity to Neuronal Nicotinic Cholinergic Receptors1”, The Journal of Pharmacology and Experimental Therapeutics, vol. 282, No. 1, 1997, pp. 445-451.
I. Khan, et al., “Epibatidine Binding Sites and Activity in the Spinal Cord”, Brain Research, vol. 753, 1997, pp. 269-282.
E. Levin, et al., “Epibatidine, A Potent Nicotinic Agonist: Effects on Learning and Memory in the Radial-Arm Maze”, Medicinal Chemistry Research, 1996, pp. 543-554.
J. Sullivan, et al., “Epibatidine: Pharmacological Properties of a Novel Nicotinic Acetylcholine Receptor Agonist and Analgesic Agent”, CNS Drug Reviews, vol. 2, No. 1, 1996, pp. 21-39.
A. Horti, et al., “Synthesis of a Radiotracer for Studying Nicotinic Acetylcholine Receptors: (+/−)-exo-2-(2-[1BF]fluoro-5-pyridyl)-7-azabicyclo[2.2.1]heptane”, Journal of Labelled Compounds and Radiopharmaceuticals, vol. 38, No. 4, 355-365.
C. Zhang, et al., “A Short and Efficient Total Synthesis of (+)-Epibatidine”, Journal of Organic Chemistry, vol. 61, 1996, pp. 7189-7191.
D. Bai, et al., “Synthesis of (+)-Epibatidine and Its Analogues”, Journal of Organic Chemistry, vol. 61, 1996, pp. 4600-4606.
R. Xu, et al., “Total Synthesis of (+)Epibatidine”, Tetrahedron Letters, vol. 37, No. 9, 1996, pp. 1463-1466.
J. Musachio, et al., “Synthesis of a Radioiodinated Analog of Epibatidine: (+/−)-exo-2-(2-iodo-5-pyridy1)-7-azabicyclo[2.2.1]heptane for in vitro and in vivo Studies of Nicotinic Acetylcholine Receptors”, Journal of Labelled Compounds and Radiopharmaceuticals, vol. 39, No. 1, pp. 39-48.
A. Sacaan, et al., “Epibatidine: A Nicotinic Acetylcholine Receptor Agonist Releases Monoaminergic Neurotransmitters: In vitro and In vivo Evidence in Rats”, The Journal of Pharmacology and Experimental Therapeutics, vol. 276, No. 2, 1996, pp. 509-515.
U. Warpman, et al., “Epibatidine and ABT 418 Reveal Selective Losses of α4β2 Nicotinic Receptors in Alzheimer Brains”, NeuroReport, vol. 6, No. 17, 1995, pp. 2419-2423.
R. Xu, et al., “Synthesis and Analgesic Activity of Epibatidine Analogues”, Bioorganic and Medicinal Chemistry Letters, vol. 6, No. 3, 1996, pp. 279-282.
C. Szantay, et al., “Epibatidine”, The Alkaloids, vol. 46, 1995, pp. 95-125.
D. Perry, et al., “[3]Epibatidine Labels Nicotinic Receptors in Rat Brain: An Autoradiographic Study1”, The Journal of Pharmacology and Experimental Therapeutics, vol. 275, No. 2, 1995, pp. 1030-1034.
G. Pandey, et al., “An Expeditious Synthesis of Epibatidine and Analogues”, Tetrahedron Letters, vol. 35, No. 40, 1994, pp. 7439-7442.
V. Gerzanich, et al., “Comparative Pharmacology of Epibatidine: A Potent Agonist for Neuronal Nicotinic Acetylcholine Receptors

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