Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-31
1998-02-03
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514352, 546261, 546262, 546305, C07D40112, A61K 3144
Patent
active
057145032
ABSTRACT:
Treatment of AIDS, inhibition of the replication of HIV and related viruses thereof, and formulations using thiourea derivative compounds or salts thereof is disclosed. Also disclosed are novel thiourea derivative compounds.
REFERENCES:
patent: Re31244 (1983-05-01), Peterson
patent: 3061640 (1962-10-01), Beaver et al.
patent: 3705903 (1972-12-01), Crank
patent: 3809755 (1974-05-01), Crank
patent: 3891769 (1975-06-01), Shea et al.
patent: 3950537 (1976-04-01), DeBenneville et al.
patent: 3950538 (1976-04-01), Shea
patent: 4036979 (1977-07-01), Asato
patent: 4048333 (1977-09-01), Galabov et al.
patent: 4057636 (1977-11-01), Peterson
patent: 4066695 (1978-01-01), Cohen et al.
patent: 4096276 (1978-06-01), Cohen et al.
patent: 4113776 (1978-09-01), Cohen et al.
patent: 4150138 (1979-04-01), Cohen et al.
patent: 4169154 (1979-09-01), Cohen et al.
patent: 4367226 (1983-01-01), Foye
patent: 4656026 (1987-04-01), Coffmann et al.
patent: 4880836 (1989-11-01), Elbaum
patent: 4994481 (1991-02-01), Zimmer et al.
Zhang, Antiviral Res. 28 (4) 331, 1995.
Kammuller et al., Int'l Jour. of Immunopharmacology, 997-1010 (1988).
Lombardino et al., Jour. of Medicinal Chemistry, 7, No. 1, 97-101 (Jan. 1964).
Ghomeim et al., Egypt. J. Pharm. Sci. 28, No. 1-4, 77-86 (1987).
Fujiwara et al., J. Chem. Soc. Perkin Trans. 2, 1573-1577 (1980).
Fujiwara et al., J. Chem. Soc. Perkin Trans. 2, 659-663 (1979).
Chemical Abstracts, 94, No. 17, p. 766, Abstract No. 139811z (Apr. 27, 1981).
Chemical Abstracts, 90, No. 7, p. 107, Abstract No. 49009g (Feb. 12, 1979).
Nowak, Roczniki Chimii, 47, No. 12, 2377-2378 (1973).
Rahman et al., Bangladesh J. Biol. Science, 5, No. 1, 28-30 (1976).
Marx et al., J. of Medicinal Chem., 13, No. 6, 1179-1181 (1970).
Mammo et al., J. of Pharmacy and Pharmacology, 34, No. 11, 752-754 (1982).
Chemical Abstracts, 110, No. 9, p. 653, Abstract No. 75501n (Feb. 27, 1989).
Horn et al., J. of Chromatography, No. 180, 111-118 (1979).
Pataki, Chimia, 18, No. 1, 23-34 (1964).
Waite, Analytical Biochemistry, 192, No. 2, 429-433 (1991).
Lilova et al., Biological Chemistry Hoppe-Seyler, 367, No. 10, 1055-1059 (1986).
Attia et al., Bull. De L'Academie Polonaise Des Sciences, 24, No. 10, 781-790 (1976).
Korohoda et al., Polish J. of Pharmacology and Pharmacy, 28, No. 5, 423-427 (1976).
Weygand et al., European J. of Biochem., 20, 72-80 (1971).
Burrell et al., Australian J. of Chem., 28, No. 10, 2289-2298 (1975).
Mahachi et al., J. of Chromatography, No. 298, 279-288 (1984).
Miyano et al., Biomedical Chromatography, 2, No. 4, 139-144 (1987).
Chemical Abstracts, 60, No. 11, p. 1964, Abstract No. 13546f (May 25, 1964).
Knoppova et al., Collection of Czech. Chemical Comm., 39, No. 3, 773-778 (1974).
Epp, Analytical Chemistry, 29, No. 9, 1283-1287 (Aug. 23, 1957).
Solyom et al., Acta Chimica Academiae Scientarum Hungaricae, 68, No. 1-2, 93-132 (1971).
Chemical Abstracts, 76, No. 23, p. 46, Abstract No. 135847w (Jun. 5, 1972).
Chemical Abstracts, 111, No. 25, p. 854, Abstract No. 233511t (Dec. 18, 1989).
Chemical Abstracts, 112, No. 7, p. 14, Abstract No. 48249w (Feb. 12, 1990).
Chemical Abstracts, 95, No. 19, p. 731, Abstract No. 16907v (Nov. 9, 1981).
Martin et al., Archiv Der Pharmazie, 296, No. 10, 641-650 (Oct. 1963).
Birr et al., Angew. Chemie, 82, No. 18, 771-772 (1970).
Morikawa et al., Agricultural and Biological Chemistry, 55, No. 11, 2751-2756 (Nov. 1991).
A. Mohsen et al., J. Pharm. Sciences, vol. 73, No. 8, (1984) pp. 1166-1168.
Ware, E., Chem. Rev., 46, 436 (1950).
Central Patents Index Country Alerting Bulletin, Section B, 1979, Week B11, 27 Apr. 79, J5 4016-467.
H. Wilitzer et al., Pharmazie 33, H.1 (1978), pp. 30-38.
Chemical Abstracts, vol. 89, 1878, p. 644 (24221m).
Chemical Abstracts, vol. 94, 1981, p. 160 (26081t).
Chemical Abstracts, vol. 96, 1982, p. 52221 (52221Z).
Synthesis, May 1983, No. 5, pp. 391-392.
Indian J. Chem., vol. 10, pp. 686-690 (Jul., 1972).
Arch. Pharm. (Weinheim), vol. 323, pp. 971-975 (1990).
Jour. Pharm. Sci., vol. 51, No. 11, pp. 1031-1033 (Nov., 1962).
Indian J. Chem., vol. 21B, pp. 750-752, (Aug., 1982).
Chemical Abstracts, vol. 81, No. 21, (Nov. 25, 1974) Abstract No. 135582j and ZH. Org. Khim., vol. 10, No. 8, pp. 1661-1669 (1974).
Chemical Abstracts, vol. 83, No. 7, (Aug. 18, 1975) Abstract No. 53854b and Yakagaku Zasshi, vol. 95, No. 4, pp. 373-377 (1975).
Chemical Abstracts, vol. 70, No. 17 (Apr. 28, 1969) Abstract No. 77857n and Yakugaku Zasshi, vol. 88, No. 11, pp. 1428-1432 (1968).
Chemical Abstracts, vol. 62, No. 9 (Apr. 26, 1965) Abstract No. 10425d and Atti Accad. Sci. Lettere Arti Palermo, Pt. I, vol. 23, pp. 139-142 (1964).
Chemical Abstracts, vol. 65 (1966) Abstract No. 2907F and Bruce, M. et al. Cytokinin activity of some substituted ureas and thioureas, pp. 249-265 (Dec. 29, 1965).
Boll. Chim. Farm., F. Russo, vol. 100, pp. 252-256 (1961).
Indian Jour. Chem., Nagarajan, K. et al., vol. 23B, pp. 342-362 (Apr. 1984).
Jour. Med. Chem., vol. 15, No. 10, pp. 1082-1084 (1972).
Indian Jour. Chem., vol. 5, No. 4, pp. 145-146 (Apr. 1967).
Jour. Indian Chem. Soc., vol. 35, No. 4, pp. 245-248 (1961).
Indian Jour. Pharm. Sci., vol. 44, No. 1, pp. 83-85 (1982).
Chemical Abstract 81: 13558Z R.N. 53578-59-9.
Lind Peter Tomas
Morin, Jr. John M.
Noreen Rolf
Ternansky Robert J.
Gerstl Robert
Medivir AB
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