Compounds and methods for diagnosis and immunotherapy of...

Details Compounds and methods for diagnosis and immunotherapy of... Compounds and methods for diagnosis and immunotherapy of...

2011-04-19

2011-04-19

Ford, Vanessa L. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S184100, C424S192100, C424S234100, C514S002600

Reexamination Certificate

active

07927611

ABSTRACT:
Compounds and methods for diagnosing tuberculosis or for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or moreMycobacteriumproteins and DNA molecules encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection ofMycobacteriuminfection in patients and biological samples. Antibodies directed against such polypeptides are also provided. In addition, such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization againstMycobacteriuminfection.

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