Compounds and methods

Details Compounds and methods Compounds and methods

1979-04-26

1980-08-19

Danison, Walter C.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 2601125R, 260121, 424 1, 424 12, 424226, 424285, 424305, 528328, A61K 3702, A61K 3900

Patent

active

042184363

ABSTRACT:
A method for the radioimmunoassay of PGE.sub.1 -type and PGE.sub.2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic.
Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule.
Antibodies are disclosed which are specific against PGE.sub.1 -type and PGE.sub.2 -type compounds, PGH.sub.2, and PGX.
Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.

REFERENCES:
patent: 3867366 (1975-02-01), Rubenstein et al.
patent: 3950363 (1976-04-01), Bundy
patent: 3980764 (1976-09-01), Adams
patent: 4041076 (1977-08-01), Avenia et al.
patent: 4053459 (1977-10-01), Christenson
Corey et al., Proc. Nat'l Acad. Sci., vol. 72, No. 9, (Sept. 1975), pp. 3355-3358.
Corey et al., J.A.C.S., vol. 199, No. 6 (Mar. 1977), pp. 2006-2008.

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