Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-05-06
2008-05-06
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S190000, C546S191000
Reexamination Certificate
active
10494195
ABSTRACT:
NK2R binding compounds in accord with structural diagram I useful for the treatment or prevention of OAB or UI in mammals, particularly humans are disclosed:wherein in said compounds D, A, R1, R3and R4are as defined in the specification. Pharmaceutically-advantageous salts of the compounds, methods of use of the compounds, either alone or in combination with other pharmacological agents, and pharmaceutical compositions useful in practicing the methods of the invention are also disclosed.
REFERENCES:
patent: 5559131 (1996-09-01), Miller
patent: 5576333 (1996-11-01), Miller
patent: 5677317 (1997-10-01), Miller
patent: 5731309 (1998-03-01), Bernstein et al.
patent: 6008223 (1999-12-01), Bernstein et al.
patent: 0630887 (1994-12-01), None
patent: WO 9505377 (1995-02-01), None
patent: WO 9628158 (1996-09-01), None
patent: WO 0020003 (2000-04-01), None
patent: WO 0025766 (2000-05-01), None
patent: WO 0034243 (2000-06-01), None
patent: WO 0197811 (2001-12-01), None
Miller et al. “4-carboxoamidopiperidine . . . ” CA 122:105675 (1995).
Miller et al. “Novel 4-piperidinyl . . . ” CA 123:143649 (1995).
Bernstein et al. “Preparation of 4-piperidinobutylamine . . . ” CA 125:58328 (1996).
Miller et al. “Preparation of N-piperidinoalkylbenzamides . . . ” CA 126:47105 (1996).
King “Bioisosteres, conformational . . . ” Med. Chem. principle & practice p. 206-208 (1994).
Patani et al. “Biuoisosterism: a rational approach . . . ” Chem. Rev. p. 3147-3176 (1996).
Bialecki Russell
Dantzman Cathy
Herzog Keith
AstraZeneca AB
Chang Celia
Pepper Hamilton LLP
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