Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-10-03
2006-10-03
Ponnaluri, Padmashri (Department: 1639)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S002600, C514S009100, C514S015800, C514S016700, C514S017400, C530S300000, C530S317000, C530S324000, C530S409000
Reexamination Certificate
active
07115566
ABSTRACT:
The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridine⇄pyridinium salt-type redox targetor moiety, a bulky lipophilic function and an amino acid/dipeptide/tripeptide spacer, are used in the prevention and treatment of diabetic retinopathy.
REFERENCES:
patent: 6440933 (2002-08-01), Bodor et al.
patent: WO 9912572 (1999-03-01), None
Bodor Nicholas Stephen
Grant Maria
Beusse Wolter Sanks Mora & Maire
Ponnaluri Padmashri
University of Florida
Van Dyke Timothy H.
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