Compounds and compositions with nitrogen-containing non-basic si

Details Compounds and compositions with nitrogen-containing non-basic si Compounds and compositions with nitrogen-containing non-basic si

1996-07-15

1997-05-20

Dees, Jos e G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514182, 514443, 514469, 514520, A61K 3156, A61K 3138, A61K 3134, A61K 31275

Patent

active

056312474

ABSTRACT:
The present invention provides compounds and pharmaceutical compositions, optionally containing estrogen or progestin, and the use of such compounds, alone, or in combination with estrogen or progestin, for inhibiting the symptoms of postmenopausal symptoms, particularly osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer.
The present invention further provides the use of the compounds of the present invention for inhibiting uterine fibroid disease and endometriosis in women, and aortal smooth muscle cell proliferation, particularly restenosis, in humans.

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