Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-06-14
1993-07-13
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 66, A61K 3144, C07D47106
Patent
active
052273830
ABSTRACT:
New analogs of sampangine and cleistopholine, compositions and methods of preparation thereof, method of treating fungal and mycobacterial infections. The compounds have the general formula: ##STR1## where the R.sub.1, R.sub.2, and R.sub.5 groups are defined herein.
REFERENCES:
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patent: 4218453 (1980-08-01), Hannart
patent: 4965272 (1990-10-01), Hufford
Hufford "Anticandidal Activity . . . ", Jour. Natural Products, vol. 50 No. 5 pp. 961-64 Sep. Oct. 1987.
Liu, et al., "3-MeO-Sampangine . . . Copyrine Alkaloid", Antimicrobial Agents and Chemotherapy Ap. 1990, pp. 529-33.
Chemical Abstracts: 113: 37723r (Liu).
Clark Alice M.
Hufford Charles D.
Liu Shihchih
Oguntimein Babajide O.
Peterson John R.
Cintins Marianne M.
Scalzo Catherine
The University of Mississippi
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