Compounds active at the glucocorticoid receptor II

Details Compounds active at the glucocorticoid receptor II Compounds active at the glucocorticoid receptor II

2007-05-22

2007-05-22

Anderson, Rebecca (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S317000, C514S365000, C514S464000, C544S171000, C546S239000, C546S342000, C548S204000, C549S447000

Reexamination Certificate

active

10433015

ABSTRACT:
This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in therapy and in the regulation of metabolism, especially lowering blood glucose levels. The compounds referred to are compounds according to the formula 1:wherein the variables are as defined herein.

REFERENCES:
patent: WO 99/63976 (1999-12-01), None
patent: WO 00/07972 (2000-02-01), None
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FDA mulls drug to slow late-stage Alzheimer's [online], [retrieved on Sep. 23, 2003]. Retrieved from the Internet,URL;http://www.cnn.com/2003/HEALTH/conditions/09/24/alzheimers.drug.ap/index.html>.

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