Compounds

Details Compounds Compounds

1995-04-05

1999-06-08

Lambkin, Deborah C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Hydroxamic acids, chalcogen analogs or salts thereof

562622, 562623, 564153, C07D 5302, C07D 5304

Patent

active

059106093

ABSTRACT:
Compounds of general Formula I: ##STR1## are presented which have collagenase inhibition activity and are useful in the management of disease involving tissue degradation and the promotion of wound healing. Representative diseases involving include arthropathy (particularly rheumatoid arthritis), inflammation, dermatological diseases, bone resorption disease and tumor invasion.

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