Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-04-30
2000-08-08
Martinell, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 435455, 536 231, 536 232, 536 235, C12P 2102
Patent
active
061000590
ABSTRACT:
HGBAB90 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HGBAB90 polypeptides and polynucleotides in the design of protocols for the treatment of pulmonary emphysema, arthritis, multiple sclerosis, periodontal disease, cystic fibrosis, respiratory disease, thrombosis, cancer, cachexia, angina, glaucoma, inflamatory disorders, osteoporosis, cardiovascular disorders such as hypertension, atherosclerotic disorders such as cardiac infarction, and stroke, asthma, psoriasis, chronic neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's, demyelinating diseases, AIDS immune deficiency, disorders of photoreceptor degeneration, and lens cataract formation, organ transplant rejection, cataracts, restenosis, muscular dystrophy, renal failure, cerebral vasospasm, pancreatitis, and diabetic nephropathy, among others, and diagnostic assays for such conditions.
REFERENCES:
GenBank Accession #P00760.
GenBank Accession #P35033.
GenBank Accession #U62801.
GenBank Accession #D30785.
HGS EST #1703154.
GenBank Accession #A90164.
Critical Synergy: The Biotechnology Industry and Intellectual Property Protection, Biotechnology Industry Organization, Washingtion, DC, Oct. 17, 1994, pp. 75 and 100-107.
Burgess Nicola Anne
Clinkenbeard Helen Elizabeth
Southan Christopher Donald
Hecht Elizabeth J.
King William T.
Martinell James
SmithKline Beecham p.l.c.
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