Compounds

Details Compounds Compounds

1993-04-05

1997-10-28

Lilling, Herbert J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 253, 536 256, 536 261, C07H 1904, C07H 2102, C07H 2100

Patent

active

056819455

ABSTRACT:
A support carrying a homocyclic or heterocyclic ring containing a first and second carbon atom wherein: (i) the first carbon atom is substituted by a nucleophilic group or a group convertible to a nucleophilic group on treatment with base; (ii) the second carbon atom is substituted by a hydroxy group, a hydroxy group protected by an acid labile protecting group, or a phosphate group substituted by an oligonucleotide; and (iii) the first and second carbon atoms are directly connected by a covalent bond; which is suitable for use in oligonucleotide synthesis. Methods for its preparation and use, and novel compounds for attachment to the support are described.

REFERENCES:
patent: 4775619 (1988-10-01), Urdea
patent: 5118605 (1992-06-01), Urdea
patent: 5378825 (1995-01-01), Cook et al.
patent: 5380833 (1995-01-01), Urdea
Sigma Chem Comp Catalogue T6647 p. 1487 Pub. 1990.
Watanabe et al "J. Chromatography" 207 (1981) 13-20.
Merck Index 10th Ed. 1983 #8928 Tannic Acid p. 1301.
Pierce 1989 Handbook & General Catalogue p. 45 Heparin on TSK HW-65W.
C.A. 110:173684 No19 (May 8, 1989) Dellinger et al.

Affiliated with

Also associated with

Rating

Compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1027190