Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-06-15
2009-06-30
Morris, Patricia L (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S114000
Reexamination Certificate
active
07553849
ABSTRACT:
A compound of formula (I)whereinR is methyl, ethyl, n-propyl, iso-propyl, n-butyl or allyl;R′ is hydrogen, C1-C4alkyl, C1-C3alkoxy; halogen, trifluoromethyl or OCHxFy,R″ is hydrogen, fluoro or chloro, that R″ being fluoro or chloro only when R′ is fluoro or chloro;R3is hydrogen or C1-C5alkylR4is hydrogen, CH2OCOC(CH3)3, pharmaceutically acceptable inorganic or organic cations, or COR4′ wherein R4′ is C1-C5alkyl, phenyl, benzyl or phenethyl;R7is methyl or ethyl;one of A and B is sulphur and the other is C-R2;when A is S, R2is selected from hydrogen and methyl, with the proviso that R2is methyl only when R3is not hydrogen; andwhen B is S, R2is hydrogen;and any tautomer thereof.A pharmaceutical composition comprising a compound of formula (I), a method of treating malignant tumours or diseases resulting from autoimmunity or pathologic inflammation.
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Björk Anders
Jansson Karl
Active Biotech AB
Browdy and Neimark , P.L.L.C.
Morris Patricia L
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